Strategic Initiative Fund (SIF) Projects

SIF Funded Projects

Primary Impact Area: Human Health & Well-Being

mi-SonoPatch: Smart Acute Abdominal Assessment

The project aims to improve how emergency departments evaluate acute abdominal pain, a leading cause of emergency room visits and CT imaging.

The Ypsilanti Health Center-Legal Services of South Central Michigan Medical-Legal Partnership (YHC-LSSCM MLP)

This initiative will integrate legal professionals into healthcare settings to address social and legal issues that negatively impact patient health.

Game Changers: The Michigan Center for Innovation in Women's Sports

Game Changers is dedicated to advancing the health, performance, and holistic well-being of female athletes across all ages, sports, and ability levels.

The Exercise Oncology Initiative (EOI)

EOI will create the first training pathway for professionals to deliver evidence-based exercise support to cancer patients and survivors.

Michigan Initiative to Reprogram Cells for Diabetes (MIRC-D)

MIRC-D’s goal is to move diabetes care beyond chronic disease management toward regenerative repair by using direct cell reprogramming.

Transformative Health Justice Training for Interprofessional Learners

This initiative will equip students in all healthcare fields to become effective agents for dismantling health inequities and medical racism.

Personalized Immune Models to Predict Infectious Disease Outcomes

This project aims to establish a personalized approach to infectious-disease prediction, treatment, and prevention.

Monitoring Food Hardship in the US

This project will track food insufficiency in U.S. households, publish quarterly briefs, and provide free public data on hardship among vulnerable families nationwide.

AI-Powered Optical Biopsy for Real-Time In Vivo Pathology

This initiative would enable clinicians to evaluate tissue microscopically during routine endoscopy rather than relying solely on physical biopsies and off-site pathology.

AI-Enabled Scalable Training for Global Mental Health Service Providers

This project will create an AI-enabled, culturally adapted platform to train and assess mental health counselors and therapists in low- and middle-income countries.

Michigan Center for Extracellular Nanomedicine (MCEN)

MCEN unites Michigan researchers to study tiny particles that shape health and engineer tools for earlier detection, precise drug delivery, and tissue healing.

Michigan Center for Human Immunology Model Systems (MiCHIM)

MiCHIM will advance fundamental discovery of how the human immune system works and better predict how new treatments will perform in people.

A Novel Strategy for Effective and Non-Addictive Pain Management

This initiative presents a novel strategy for effective, non-addictive pain management aimed at addressing the public health and economic burden of acute and chronic pain.

Primary Impact Area: Advanced Technology

Mi DuRAG: Human-Centered AI for Data Analysis in Research and Education

Mi DuRAG aims to create an AI data partner that captures expert decisions, rationales, and data structure, allowing students and researchers to focus on analytical questions.

Detroit Small Business Innovation & Learning Hub

The hub will equip Detroit small businesses with the digital tools they need to run smarter, while giving U-M students real experience building and deploying technology.

The Michigan Deepfake Resilience Hub

M-DRH combines explainable AI, human-centered design, and education to help the public understand AI-generated contents and protect themselves against AI-generated fraud.

Battery Safety and Sustainability Research and Testing Center

The center will establish the first open-access EV battery thermal-runaway testing facility to support research that helps prevent thermal failure and advances transportation.

Center of Safety for All (Safety4All)

The Safety4All Center will develop digital human twins and virtual testing technologies that fundamentally transform how safety systems are designed and evaluated.

Integrated Photonics for Low-Cost At-Home Biomarker Sensors

This initiative will develop low-cost, at-home biosensors to provide early disease detection, enable timely intervention, and improve quality of life for two chronic diseases.

Center for Human–Agentic AI Collaboration for Urban Resilience

This initiative brings together U-M researchers with community partners to strengthen urban resilience against flooding, severe weather, and water infrastructure failures.

Great Lakes Maritime Initiative

The Great Lakes Maritime Initiative will position the Great Lakes as a national hub for shipbuilding revitalization, maritime innovation, and workforce development.